Contrave dosage: What you need to know before you start

If you’ve heard about Contrave for weight loss, the first question is usually “how much should I take?”. The answer isn’t a one‑size‑fits‑all number – it depends on your health, how your body reacts, and the doctor’s plan. This guide breaks down the usual dosing schedule, why doctors start low, and the signs that tell you you’re on the right track.

How to take Contrave – the typical titration plan

Contrave comes as a combination of bupropion and naltrexone. Most prescribers begin with one tablet a day for the first week. This low dose lets your system adjust and helps reduce early side effects like nausea. After seven days, the dose usually goes up to two tablets a day – one in the morning, one in the evening.

Some people tolerate the medication well and stay at two tablets daily. Others need the full three‑tablet regimen (one tablet three times a day) to get the best weight‑loss effect. Your doctor will decide whether to push toward the higher dose based on your progress and any side effects you report.

Never skip doses or double up without checking your provider. If you miss a dose, take it as soon as you remember unless it’s almost time for the next one – then just skip the missed pill and continue with the regular schedule.

What to watch for while you’re on Contrave

Side effects are most common in the first two weeks. Nausea, headache, dry mouth, and constipation pop up for many users. These usually fade as your body gets used to the medication. If you notice severe dizziness, rapid heartbeat, or mood changes, call your doctor right away.

Because Contrave affects the brain’s reward pathways, it can interact with other drugs that also raise seizure risk, like certain antidepressants. Always tell your healthcare team about every medication you’re taking, including over‑the‑counter supplements.

Weight loss results vary. Most studies show a 5‑10% reduction in body weight after about six months when the medication is taken as prescribed and paired with diet changes. If you’re not seeing any change after a few months, discuss adjustments with your doctor – sometimes a higher dose or a different weight‑loss plan is needed.

Finally, keep an eye on liver health. Though rare, there have been reports of elevated liver enzymes. Your doctor may order blood tests before starting Contrave and periodically afterward to make sure everything’s okay.

In short, the standard Contrave dosage starts low, climbs to two tablets a day, and may go up to three tablets if needed. Watch for side effects, stay in touch with your prescriber, and combine the medication with a healthy eating plan for the best chance at lasting weight loss.